Changing our drinking water with a new solution
I was traveling last week for my other company, TwinOxide, in Louisiana and Arkansas. We were conducting the final series of jar tests using our TwinOxide chlorine dioxide that is ultra pure (99.9%) and therefore has no free chlorine in the final product. This is huge for drinking water as it is free chlorine that combines with organics to form the carcinogenic byproducts known as Trihalomethane s (THM). The town we were in is replacing chlorine gas and all the associated hazards with TwinOxide for disinfection of their drinking water. Currently, that plant has very high THM levels. The progressive solution involving using a completely different disinfectant is a new and creative way to use science to their advantage to achieve their goal of better, safer water for the community.
Science of all sorts can be creative and unique. The theory of today becomes the fact of tomorrow as experiments test out the proposals and determine what was correct, what was close and what was not even in the same ballpark. It is the presentation of alternative theories that generates curiosity and testing to prove or disprove the newest theory on a subject.
Alzheimer’s disease is caused by a bacteria in humans
Veerasak (Jeep) Srisuknimit from Harvard puts forth that Alzheimer’s disease is caused by a bacteria in humans. The entire blog can be found at this link: http://sitn.hms.harvard.edu/flash/2019/oral-bacteria-may-responsible-alzheimers-disease/
Alzheimer’s disease is the leading cause of dementia. It progressively worsens multiple aspects of health over time, from short-term memory loss to behavioral changes to loss of bodily functions. The actual cause of Alzheimer’s is currently unknown. One widely-accepted hypothesis proposes that Alzheimer’s is caused by the accumulation of misfolded proteins in the brain. Unfortunately, many drugs targeting misfolded proteins perform poorly in clinical trials, hinting that this hypothesis might be wrong. Misfolded proteins might be another side effect, not the cause.
Highlights of this theory include:
Researchers recently published a new line of evidence supporting a hypothesis that Alzheimer’s might be a result of an infection by oral bacteria P. gingivalis.
The bacteria produces toxins called gingipains that are found to accumulate in the brain of Alzheimer’s patients. The gingipains degrade human proteins, giving rise to the infamous misfolded proteins.
The researchers also developed chemical compounds that could neutralize gingipains. Mice injected with gingipains developed degenerate brain cells, while mice that were pretreated with neutralizing compounds beforehand maintained healthy brain cells.
Although this new work might be the much-needed breakthrough in curing Alzheimer’s disease, the hypothesis is not conclusively proven and many questions still remain. Is P. gingivalis actually the cause of Alzheimer’s? Some experts still believe the disease could be caused by a fungal or viral infection. How does the bacteria get from the gum to the brain? What else does the gingipain toxin interact with in the brain? Are the neutralizing compounds safe or even effective in humans?
What do you think? Can bacteria really be the source of such a chronic debilitating disease? Can the disease be prevented by more carefully managing the populations of bacteria that live within us?
Write a response and let’s compare notes.
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